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Peripheral Neuropathy

Peripheral Neuropathy

What is Diabetic Peripheral Neuropathy?
neuropathy is nerve damage caused by diabetes. When it affects the
arms, hands, legs and feet it is known as diabetic peripheral
neuropathy. Diabetic peripheral neuropathy is different from peripheral
arterial disease (poor circulation), which affects the blood vessels
rather than the nerves.

Three different groups of nerves can be affected by diabetic neuropathy:

  • Sensory nerves, which enable people to feel pain, temperature, and other sensations
  • Motor nerves, which control the muscles and give them their strength and tone
  • Autonomic nerves, which allow the body to perform certain involuntary functions, such as sweating.

Diabetic peripheral neuropathy doesn’t emerge overnight. Instead, it
usually develops slowly and worsens over time. Some patients have this
condition long before they are diagnosed with diabetes. Having diabetes
for several years may increase the likelihood of having diabetic

The loss of sensation and other problems associated with nerve damage
make a patient prone to developing skin ulcers (open sores) that can
become infected and may not heal. This serious complication of diabetes
can lead to loss of a foot, a leg, or even a life.

The nerve damage that characterizes
diabetic peripheral neuropathy is more common in patients with poorly
managed diabetes. However, even diabetic patients who have excellent
blood sugar (glucose) control can develop diabetic neuropathy. There are
several theories as to why this occurs, including the possibilities
that high blood glucose or constricted blood vessels produce damage to
the nerves.

As diabetic peripheral neuropathy progresses, various nerves are
affected. These damaged nerves can cause problems that encourage
development of ulcers. For example:

  • Deformities (such as bunions or hammertoes) resulting from motor
    neuropathy may cause shoes to rub against toes, creating a sore. The
    numbness caused by sensory neuropathy can make the patient unaware that
    this is happening.
  • Because of numbness, a patient may not realize that he or she has stepped on a small object and cut the skin.
  • Cracked skin caused by autonomic neuropathy, combined with sensory
    neuropathy’s numbness and problems associated with motor neuropathy can
    lead to developing a sore.

Depending on the type(s) of nerves involved, one or more symptoms may be present in diabetic peripheral neuropathy.

For sensory neuropathy:

  • Numbness or tingling in the feet
  • Pain or discomfort in the feet or legs, including prickly, sharp pain or burning feet

For motor neuropathy:

  • Muscle weakness and loss of muscle tone in the feet and lower legs
  • Loss of balance
  • Changes in foot shape that can lead to areas of increased pressure

For autonomic neuropathy:

  • Dry feet
  • Cracked skin

To diagnose diabetic peripheral
neuropathy, the foot and ankle surgeon will obtain the patient’s history
of symptoms and will perform simple in-office tests on the feet and
legs. This evaluation may include assessment of the patient’s reflexes,
ability to feel light touch, and ability to feel vibration. In some
cases, additional neurologic tests may be ordered.

First and foremost, treatment of
diabetic peripheral neuropathy centers on control of the patient’s blood
sugar level. In addition, various options are used to treat the painful

Medications are available to help relieve specific symptoms, such as
tingling or burning. Sometimes a combination of different medications is

In some cases, the patient may also undergo physical therapy to help reduce balance problems or other symptoms.

The patient plays a vital role in
minimizing the risk of developing diabetic peripheral neuropathy and in
preventing its possible consequences. Some important preventive measures

  • Keep blood sugar levels under control.
  • Wear well-fitting shoes to avoid getting sores.
  • Inspect your feet every day. If you notice any cuts, redness,
    blisters, or swelling, see your foot and ankle surgeon right away. This
    can prevent problems from becoming worse.
  • Visit your foot and ankle surgeon on a regular basis for an examination to help prevent the foot complications of diabetes.
  • Have periodic visits with your primary care physician or
    endocrinologist. The foot and ankle surgeon works together with these
    and other providers to prevent and treat complications from diabetes.


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